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Mifepristone

BML-S510

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Progesterone receptor ligand

Progesterone receptor antagonist.

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Product Details

Alternative Name	RU 486
Appearance	Yellow solid.
CAS	84371-65-3
Couple Target	Progesterone receptor
Couple Type	Ligand
Formula	C₂₉H₃₅NO₂
MW	429.6
Purity	≥99% (Assay)
Solubility	Soluble in methanol or DMSO.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Progesterone modulates the LPS-induced nitric oxide production by a progesterone-receptor independent mechanism: M.L. Wolfson, et al.; Eur. J. Pharmacol. 769, 110 (2015), Application(s): Cell culture, Abstract
Altered autophagic flux enhances inflammatory responses during inflammation-induced preterm labor: Agrawal, V., Jaiswal, M. K., et al.; Sci. Rep. 5, 9410 (2015), Abstract
Glucocorticoid receptor antagonism as a novel therapy for triple-negative breast cancer: Skor, M. N., Wonder, E. L., et al.; Clin. Cancer Res. 19, 6163 (2013), Abstract

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Last modified: May 29, 2024

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