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How should I handle waxy or low-melting point solids?
Compounds with relatively low melting points will often appear to be either waxy or sticky solids. These materials are difficult…
Tue, Jul 18, 2023
How should I dissolve a peptide and store aliquots?
Peptides should be stored at -20 °C for maximum stability. Because peptides are often hygroscopic, and water content can significantly…
Tue, Jul 18, 2023
The datasheet for my compound states that it will dissolve at a certain concentration, but I still see solid material. What should I do?
In most cases the speed at which a crystalline solid will dissolve is dependent upon three main factors, the affinity…
Tue, Jul 18, 2023
My compound dissolved well into DMSO, but when I tried to dilute this DMSO stock solution with aqueous media precipitate formed. What should I do?
It is common for compounds to precipitate when a stock solution in a solvent such as DMSO is diluted with…
Tue, Jul 18, 2023
The datasheet for my compound states to add BSA or serum to the aqueoussolution before attempting to dilute my stock solution. Why is this suggested?
BSA and other serum albumins are natural carrier proteins for hydrophobic small molecules such as hormones and fatty acids. They…
Tue, Jul 18, 2023
How can I dissolve lipids for use in cell culture or other biological experiments?
Most lipids are strongly hydrophobic compounds, and working with them in an aqueous media such as for cell or tissue…
Tue, Jul 18, 2023
How should I store my peptide?
Please store any product as received according to storage recommendations listed on the product website, dataheet, or product label. Peptides…
Tue, Jul 18, 2023
What is the recommended assay concentration range for KillerTRAIL™ and SuperKillerTRAIL™?
The recommended working dilution range for KillerTRAIL™ is 10-100 ng/ml, and 2-100 ng/ml for SuperKillerTRAIL™. However, adjustment may be necessary for the end-user’s specific…
Tue, Jul 18, 2023
Why was my activation of SIRT1 by resveratrol not as strong as expected?
The kinetics of the reaction require some optimization. The optimal incubation time for the reaction can vary depending on concentrations…
Tue, Jul 18, 2023
What are the differences between TRAIL, KillerTRAIL™ and SuperKillerTRAIL™?
To induce apoptosis, TRAIL needs to form multimers, showing increasing activity with increasing multimerization levels. Multimerization of TRAIL can be…
Tue, Jul 18, 2023