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DNA, (purified) (DNAse I activated)

ALX-840-040

5 citations

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DNA, (purified) (DNAse I activated) image — **Figure:** Agarose gel of DNA (purified) (DNAse I activated) (Prod. No. ALX-840-040) (Lot L20796).”””,DNA

Product Details

Application Notes	For use with PARP-1 (Prod. No. ALX-201-063) or PARP-2 (Prod. No. ALX-201-064) in vitro activity tests. For details please see protocol.
Concentration	0.2mg/ml
Formulation	Liquid. In TRIS-EDTA.
Purity	≥99% (SDS-PAGE)
Source	Purified from calf thymus and activated by digestion with DNAse I.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	+4°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Parp3 assists muscle function and skeletal muscle differentiation by selectively adjusting H3K27me3 enrichment: Yildirim, Z., Noll, A., et al.; iScience 28, 112267 (2025), Abstract
PARP1 associates with R-loops to promote their resolution and genome stability: Laspata, N., Kaur, P., et al.; Nucleic Acids Res. 51, 2215 (2023), Abstract
PARP3 supervises G9a-mediated repression of adhesion and hypoxia-responsive genes in glioblastoma cells: L.N. Zebaze, et al.; Sci. Rep. 12, 15534 (2022), Abstract
Detection of the nuclear poly(ADP-ribose)-metabolizing enzymes and activities in response to DNA damage: Amé, J. C., Hakmé, A., et al.; Methods Mol. Biol. 464, 267 (2008), Abstract
PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase: J.C. Ame, et al.; J. Biol. Chem. 274, 17860 (1999), Abstract — Full Text

Related Products

Available

PARP-1 (human), (recombinant) (high purity)

ALX-201-063

14 citations

Alternative Name	Poly(ADP-ribose) polymerase 1
Purity	≥99% (SDS-PAGE)
Source	Produced in Sf9 insect cells. Produced in a baculovirus expression system.

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PARP-2 (mouse), (recombinant) (high purity)

ALX-201-064

5 citations

Alternative Name	Poly(ADP-ribose) polymerase 2
Purity	≥98% (SDS-PAGE)
Source	Produced in Sf9 insect cells (full length). Produced in a baculovirus expression system.

Last modified: May 29, 2024

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DNA, (purified) (DNAse I activated)

ALX-840-040

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

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