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PARP polyclonal antibody

BML-SA253

6 citations

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This antibody is covered by our Worry-Free Guarantee.

PARP polyclonal antibody Western blot — Western Blot Analysis of the Poly(ADP-ribose) polymerase, pAb (BML-SA253). Lane 1: Molecular Weight Marker, Lane 2: Human HL60 Cell Extract (BML-SW101).

Product Details

Alternative Name	Poly(ADP-ribose) polymerase, PARP-1
Application	ELISA, WB
Application Notes	Detects a band of ~116kDa by Western blot.
Formulation	Liquid. Neat serum containing 0.05% sodium azide.
Host	Rabbit
Immunogen	Synthetic peptide corresponding to aa 509-524 of bovine PARP automodification domain.
Recommendation Dilutions/Conditions	Western Blot (1:1,000, colorimetric). Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application
Source	Whole rabbit serum.
Species Reactivity	Bovine, Human, Mouse, Rat
UniProt ID	P18493
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Handling & Storage

Handling	Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Long Term Storage	-20°C
Shipping	Dry Ice

Regulatory Status	RUO – Research Use Only

Cytotoxicity of Thioalkaloid-Enriched Nuphar lutea Extract and Purified 6,6′-Dihydroxythiobinupharidine in Acute Myeloid Leukemia Cells: The Role of Oxidative Stress and Intracellular Calcium: Muduli, S., Golan-Goldhirsh, A., et al.; Pharmaceuticals (Basel) 15, (2022), Abstract
Structure-Activity Relationship of Hydroxycinnamic Acid Derivatives for Cooperating with Carnosic Acid and Calcitriol in Acute Myeloid Leukemia Cells: A. Trachtenberg, et al.; Biomedicines 9, 1517 (2021), Application(s): WB / Reactant(s) Human, Abstract
Synergistic cytotoxicity of methyl 4-hydroxycinnamate and carnosic acid to acute myeloid leukemia cells via calcium-dependent apoptosis induction: A. Trachtenberg, et al.; Front. Pharmacol. 10, 507 (2019), Application(s): WB / Reactant(s): Human, Abstract — Full Text
Cancer-selective cytotoxic Ca2+ overload in acute myeloid leukemia cells and attenuation of disease progression in mice by synergistically acting: S. Pesakhov, et al.; Oncotarget 7, 31847 (2016), Application(s): Western-blot, Abstract — Full Text
Gestational diabetes mellitus alters apoptotic and inflammatory gene expression of trophobasts from human term placenta: T.R. Magee, et al.; J. Diabetes Complications 28, 448 (2014), Application(s): Western-blot, Abstract — Full Text
Increased PARP-1 association with DNA in alkylation damaged, PARP-inhibited mouse fibroblasts: P.S. Kedar, et al.; Mol. Cancer Res. 10, 360 (2012), Application(s): WB / Reactant(s): Mouse, Abstract — Full Text

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HL60 Cell Extract (non-induced)

BML-SW101

PARP-1 monoclonal antibody (C-2-10) (affinity purified)

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36 citations

Alternative Name	Poly(ADP-ribose) polymerase-1
Application	ELISA, ICC, WB
Host	Mouse
Isotype	IgG1
Species Reactivity	Bovine, Hamster, Human, Monkey, Mouse, Rat

PARP-1 monoclonal antibody (C-2-10)

BML-SA250

26 citations

Alternative Name	Poly(ADP-ribose) polymerase-1
Application	ELISA, IHC, WB
Host	Mouse
Isotype	IgG1
Species Reactivity	Bovine, Hamster, Human, Monkey, Mouse, Rat

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PARP polyclonal antibody

BML-SA253

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Handling & Storage

Datasheet, Manuals, SDS & CofA

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