HIGHDEF^® red IHC chromogen (AP, plus)

IHC, ISH (in situ hybridization)

HIGHDEF^® red IHC chromogen (AP, plus) substrate buffer and chromogen, Empty mixing bottle

Traditional formulations for red alkaline phosphatase chromogens are unstable upon mixing. This can be problematic for use in automated slide strainers. The HIGHDEF^® red IHC chromogen (AP, plus) has been formulated for on-slide and on-board mixing for any autostainer. Both components are stable and can be loaded at the beginning of the staining run, for walk away convenience. It produces a red color, ranging from pink to brilliant dark red and is insoluble in organic solvents; therefore sections can be dehydrated in alcohol, cleared in xylene (or a xylene-substitute), and permanently mounted. This chromogen substrate system may be used for both automation and manual use.