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| Alternative Name | FLICE |
|---|---|
| Application | IHC (PS), IP, WB |
| Host | Mouse |
| Isotype | IgG2b |
| Species Reactivity | Human |
KillerTRAIL™ Protein (soluble) (human), (recombinant)
ALX-201-073
Enhanced ligand that utilizes the proprietary Killer™ linker peptide that promotes stability.
| Alternative Name | Apo-2L, TNFSF 10, CD253 |
|---|---|
| Purity | ≥99% (SDS-PAGE, MS analysis) |
| Source | Produced in E. coli. The extracellular domain of human TRAIL (aa 95-281) is fused at the N-terminus to a His-tag and a linker peptide. |
SUPERKILLERTRAIL® Protein (soluble) (human), (recombinant)
ALX-201-115
Enhanced ligand with improved stability providing significantly enhanced immune activation.
| Alternative Name | TNFSF 10, Apo-2L, CD253 |
|---|---|
| Purity | ≥98% (SDS-PAGE). MS analysis, <1% impurity (mainly Hsp70 protein from E. coli) |
| Source | Produced in E. coli. The extracellular domain of human TRAIL (aa 95-281) is fused at the N-terminus to a His-tag and a linker peptide. The active multimeric conformation is stabilized by an inserted mutation allowing an additional CC-bridge. |
| Application | IHC (PS), WB |
|---|---|
| Host | Rabbit |
| Species Reactivity | Bovine, Chicken, Dog, Guinea pig, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat, Yeast |
| Alternative Name | Apo-2L, TNFSF 10, CD253 |
|---|---|
| Purity | ≥95% (SDS-PAGE) |
| Source | Produced in E. coli. Human TRAIL (aa 114-281) is fused to a His-tag. |
| Alternative Name | 4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole |
|---|---|
| CAS | 152121-47-6 |
| Couple Type | Inhibitor |
| Purity | ≥97% (HPLC) |