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Furin convertase inhibitor (chloromethylketone)
ALX-260-022
Highly specific, potent, irreversible, and cell-permeable competitive inhibitor of proprotein convertases.
| Purity | ≥95% (HPLC) |
|---|
| Alternative Name | Tumor necrosis factor-α, TNFSF 2 |
|---|---|
| Purity | ≥95% (SDS-PAGE) |
| Source | Produced in E. coli. The extracellular domain of human TNF-α (tumor necrosis factor-α) (aa 85-223) is fused at the N-terminus to a linker peptide (8 aa) and a FLAG®-tag. |
| CAS | 56092-81-0 |
|---|---|
| Purity | ≥90% (HPLC, TLC) |
| Alternative Name | BimEL, BimL, BCL2-like |
|---|---|
| Application | IHC, WB |
| Host | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Application | Colorimetric detection, ELISA |
|---|---|
| Assay Time | 4 hours |
| Sensitivity | 5.63 pg/ml (range 11.7 - 3,000 pg/ml) |
| Species Reactivity | Species independent |
| Application | Colorimetric detection, ELISA |
|---|---|
| Assay Time | 4 hours |
| Sensitivity | 5.63 pg/ml (range 11.7 - 3,000 pg/ml) |
| Species Reactivity | Species independent |
MEGACD40L® Protein (soluble) (human), (recombinant)
ALX-522-110
High activity, high purity CD40L protein for co-stimulatory activation of an immune response
| Alternative Name | CD40L:ACRP30headless, CD154:ACRP30headless, TNFSF 5:ACRP30headless, gp39:ACRP30headless |
|---|---|
| Purity | ≥90% (SDS-PAGE) |
| Source | Produced in CHO cells. The extracellular domain of human CD40L (CD154) (aa 116-261) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag. |
Rapamycin
BML-A275
An mTOR inhibitor that modulates cell growth, proliferation, and autophagy - frequently used in signaling pathway research and immunosuppressive studies.
| Alternative Name | Sirolimus, AY-22,989, RAPA, Rapamune |
|---|---|
| CAS | 53123-88-9 |
| Couple Type | Inhibitor, Ligand |
| Purity | ≥98% (HPLC) |