The ZytoDot ® 2C SPEC DDIT3 Break Apart Probe is designed to detect translocations involving the chromosomal region 12q13.3 harboring the DDIT3 gene in tissue sections or cell samples. DDIT3 is consistently rearranged in myxoid liposarcomas (MLS). The most frequent translocation involving the DDIT3 gene region is t(12;16)(q13.3;p11.2) and occurs in about 90% of patients with MLS.
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