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Proteasome 20S β2 subunit monoclonal antibody (MCP168)

BML-PW8145

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BML-PW8145-0025 — 25 µl Inquire for Availability

$169.00

Proteasome 20S β2 subunit monoclonal antibody (MCP168) quantity
BML-PW8145-0100 — 100 µl Available

$510.00

Proteasome 20S β2 subunit monoclonal antibody (MCP168) quantity

Various systems for the nomenclature of the proteasome subunits have been established. This may be a source of confusion as the system on UniProt differs from “standard” nomenclature as described in the literature. The UniProt ID and Gene Name will help to clearly identify the proteins.

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This antibody is covered by our Worry-Free Guarantee.

Proteasome 20S beta2 subunit monoclonal antibody (MCP168) Western Blot — Western Blot analysis of BML-PW8145: Lane 1: SeeBlueTMPlus2 MW Marker, Lane 2: HeLa cell lysate (Prod. No. ADI-LYC-HL100), Lane 3: Jurkat cell lysate (Prod. No. ADI-LYC-JK100).

Product Details

Alternative Name	Proteasome subunit β type-7, Macropain chain Z
Application	IHC, WB
Clone	MCP168
Formulation	Liquid. In PBS containing 10mM sodium azide.
Gene/Protein Identifier	PSMB7 (gene name)
Host	Mouse
Immunogen	Dinitrophenylated proteasomes.
Isotype	IgG1
Purity Detail	Protein G-affinity purified ascites.
Source	Purified from hybridoma tissue culture supernatant.
Species Reactivity	Human, Yeast
Specificity	Recognizes the β2 subunit of proteasome 20S.
UniProt ID	Q99436
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Handling & Storage

Handling	Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Loss-of-function mutations in the dystonia gene THAP1 impair proteasome function by inhibiting PSMB5 expression.: Ramage, D. E., Grant, D. W., et al.; Nat. Commun. 16, 1511 (2025), Reactant(s): Human, Abstract
Oleuropein enhances proteasomal activity and reduces mutant huntingtin-induced cytotoxicity.: Huang, Z. N., Lee, S. Y., et al.; Front. Pharmacol. 15, 1459909 (2024), Application(s): WB / Reactant(s): Mouse, Abstract
Loss-of-function mutations in the dystonia gene THAP1 impair proteasome function by inhibiting PSMB5 expression: Ramage, D. E., Grant, D. W., et al.; bioRxiv , (2024), Reactant(s): Human
Healthspan improvement and anti-aggregation effects induced by a marine-derived structural proteasome activator: M.A. Vasilopoulou, et al.; Redox Biol. 56, 10262 (2022), Abstract
The role of cycloastragenol at the intersection of NRF2/ARE, telomerase, and proteasome activity.: Yılmaz, S., Bedir, E., et al.; Free Radic. Biol. Med. 188, 105 (2022), Application(s): ChIP / Reactant(s): Human, Abstract
The role of Cycloastragenol at the intersection of Nrf-2/ARE, telomerase, and proteasome activity: Kırmızıbayrak, P. B., Yılmaz, S., et al.; bioRxiv , (2022), Reactant(s): Human
Curative Treatment of POMP-Related Autoinflammation and Immune Dysregulation (PRAID) by Hematopoietic Stem Cell Transplantation: A. Meinhardt, et al.; J. Clin. Immunol. 41, 1664 (2021), Abstract
Proteasome Subunits Differentially Control Myeloma Cell Viability and Proteasome Inhibitor Sensitivity.: Stewart, W., Shi, C. X., et al.; Mol. Cancer Res. 18, 1453 (2020), Application(s): WB / Reactant(s): Human, Abstract
Novel cell line models to study mechanisms and overcoming strategies of proteasome inhibitor resistance in multiple myeloma: D. Brunnert, et al.; Biochim. Biophys. Acta Mol. Basis Dis. 1865, 1666 (2019), Abstract
Activity-Dependent Degradation of the Nascentome by the Neuronal Membrane Proteasome: K.V. Ramachandran, et al.; Mol. Cell 71, 169 (2018), Abstract — Full Text

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HeLa, (cell lysate)

ADI-LYC-HL100

1 citation

Source	Human

Last modified: May 29, 2024

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Proteasome 20S β2 subunit monoclonal antibody (MCP168)

BML-PW8145

Product Details

Handling & Storage

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