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Notes
Choosing your fixation, embedding, and antigen retrieval method for successful IHC
Immunohistochemistry (IHC) is a powerful and routinely used technique for the detection, localization, and scoring of cellular macromolecules in fixed…
Mon, Feb 06, 2023
How to Select & Optimize Primary Antibodies for IHC?
Immunohistochemistry (IHC) is a widely used technique to analyze the anatomy of the tissue of interest and to visualize the…
Mon, Feb 06, 2023
Hybridization Techniques in Cytogenetics – FISH or CGH?
Cytogenetics describes the study of chromosome structure. The earliest cytogenetic studies involved visualization and counting of whole chromosomes. Chromosome analysis…
Mon, Feb 06, 2023
FISH Testing in Cancer
Cancer refers to a complex and heterogeneous group of diseases characterized by the uncontrolled and disorderly proliferation of cells, which…
Mon, Feb 06, 2023
Why Study Cell Viability, Cell Proliferation and Cytotoxicity?
Cell-based assays are the main stay in drug discovery projects, where collections of compounds are screened to assess effects on…
Mon, Feb 06, 2023
What is the difference between Th1- and Th2- T cells?
Lymphocytes T (or T cells) are key mediators of adaptive immunity, the part of the immune system capable of generating…
Mon, Feb 06, 2023
Tools to study adaptive and innate immune response
Basics of Immunity Even though the most sophisticated immunity mechanisms are those of vertebrates, some sort of innate defense is…
Mon, Feb 06, 2023
Drug toxicity screening using induced pluripotent stem cells and high-content analysis
Toxicity, and more specifically hepatotoxicity, is a major concern for the pharmaceutical industry. Both drug candidates and approved drugs face…
Mon, Feb 06, 2023
Can You Regrow Your Brain?
It is upon us – the zombie apocalypse. Some greedy corporation has tinkered with things they should have left untouched,…
Mon, Feb 06, 2023
What is in situ hybridization and what are the recent advancements with this indispensable technique?
In situ hybridization (ISH) is a widely used method to localize and quantify DNA or RNA in cytological preparations (metaphase…
Mon, Feb 06, 2023