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Life Sciences
How can RNA degradation in the sample be prevented?
When RNA is the target of ISH, preservation of RNA in the sample is very important given the ubiquitous presence…
Tue, Jul 18, 2023
Tissue specimen preparation – How should samples be stored and for how long?
While whole tissue specimen are sometimes used for long-term storage, most often glass slide-mounted tissue sections are stored at 4°C.…
Tue, Jul 18, 2023
What is the recommended thickness of the section to perform ISH?
Ideal section thickness depends on fixation and embedding method, as well as microscope that is available. FFPE tissue is ideally…
Tue, Jul 18, 2023
Probe Design and Generation – How are DNA probes prepared?
First choice is to explore if commercially ready-to-use probes are available for specific targets. Enzo Life Sciences offers a selection…
Tue, Jul 18, 2023
Can you please explain what the SCREEN-WELL® compound libraries are used for?
In general terms, a laboratory or company interested in high-throughput screening for drug discovery will have already established an assay…
Tue, Jul 18, 2023
Which plates are used to package the SCREEN-WELL® compound libraries?
The SCREEN-WELL® compound libraries are packaged using deep-well 96-well plates from either Corning Costar (Prod. Ref. 3959) or Thermo Matrix…
Tue, Jul 18, 2023
Can I customize the SCREEN-WELL® compound library I am interested in?
SCREEN-WELL® compound libraries can be customized to fit your experimental requirements (384-well plate, cherry-picking, smaller volume, etc.). Please feel free…
Tue, Jul 18, 2023
Can I have the IC50 values of the compounds included in your SCREEN-WELL® compound libraries?
Regretfully, we do not test for IC50 values. IC50 values are not always available and when they are, they apply…
Tue, Jul 18, 2023
General handling, storage instructions, and stability of the SCREEN-WELL® compound libraries
Compound libraries should be thawed at room temperature. Once thawed, the plates can be gently centrifuged to bring down any…
Tue, Jul 18, 2023
How should I dilute my SCREEN-WELL® compound library for my assay?
Each one of the compounds are supplied at a concentration of 10 mM in DMSO, unless stated otherwise. In high-throughput…
Tue, Jul 18, 2023