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Knowledge Base
What is the purity of the compounds included in your SCREEN-WELL® Natural product library (BML-2865)?
Compounds in our SCREEN-WELL® Natural product library (BML-2865) are 85% pure or better (with most of the compounds coming in…
Tue, Jul 18, 2023
Can you please explain what the SCREEN-WELL® compound libraries are used for?
In general terms, a laboratory or company interested in high-throughput screening for drug discovery will have already established an assay…
Tue, Jul 18, 2023
General handling, storage instructions, and stability of the SCREEN-WELL® compound libraries
Compound libraries should be thawed at room temperature. Once thawed, the plates can be gently centrifuged to bring down any…
Tue, Jul 18, 2023
Can I customize the SCREEN-WELL® compound library I am interested in?
SCREEN-WELL® compound libraries can be customized to fit your experimental requirements (384-well plate, cherry-picking, smaller volume, etc.). Please feel free…
Tue, Jul 18, 2023
How should I dilute my SCREEN-WELL® compound library for my assay?
Each one of the compounds are supplied at a concentration of 10 mM in DMSO, unless stated otherwise. In high-throughput…
Tue, Jul 18, 2023
Can I have the IC50 values of the compounds included in your SCREEN-WELL® compound libraries?
Regretfully, we do not test for IC50 values. IC50 values are not always available and when they are, they apply…
Tue, Jul 18, 2023
Which software can I use to open the SD files that come with the SCREEN-WELL® compound libraries?
Structure files (or SD files) can be opened using the ISIS/BASE software. ISIS/BASE is the only program that can read…
Tue, Jul 18, 2023
How many compounds in your SCREEN-WELL® Neurotransmitter library (BML-2810) are clinically approved?
We did an overlap analysis of our SCREEN-WELL® Neurotransmitter library (BML-2810) with our SCREEN-WELL® FDA-approved drug library (BML-2843) and there…
Tue, Jul 18, 2023
How many compounds in your SCREEN-WELL® Kinase inhibitor library (BML-2832) are FDA-approved?
We have cross-listed the compounds included in our SCREEN-WELL® kinase inhibitor library (BML-2832) with the compounds included in our SCREEN-WELL®…
Tue, Jul 18, 2023
How long should I incubate my LEADING LIGHT® Wnt reporter cells after adding the luciferase substrate?
Signals should be read 10 minutes after adding the luciferase substrate with a multichannel pipette. The signal is stable enough…
Tue, Jul 18, 2023