DNA Modifications

Ensure Accuracy in DNA Methylation Analysis

Convenient Kits for Sample Conversion and Detection

DNA methylation can alter gene expression, cell differentiation, and often results in unidirectional changes to genomic DNA. Its involvement in so many cellular processes means errors resulting in abnormal DNA methylation patterns can lead to disease. Expanding our expertise in epigenetic modification analysis, Enzo now offers a portfolio of products that enable detection of DNA methylation.

Sample Conversion

High-efficiency Conversion of 5-mC and 5-hmC DNA for the Truest Downstream Analysis

Complete Product Range
  • Conversion allows for resolution of single nucleotide information
  • Kits provide high conversion rates without the introduction of DNA damage
  • Converted output sample suitable for detection by
    • bisulfite sequencing
    • methylation-specific PCR
    • high resolution melting curve analysis
    • microarray-based approaches
    • next-generation sequencing

DNA Methylation Detection

Colorimetric Assay Based Detection
DNMT Colorimetric Drug Discovery Kit

Rapid, sensitive, and simple colorimetric DNMT activity/inhibition kit.

ELISA-Based Detection
5-Methylcytosine DNA ELISA kit
  • Accurately quantitate 5-mC in any DNA sample in less than 3 hours
  • Ideal for high-throughput analysis
  • High specificity comparable to LC-MS/MS-MRM analysis
Complete Product Range