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Immune & Inflammation Signaling
MEGACD40L® Protein (soluble) (human), (recombinant)
ALX-522-110
High activity, high purity CD40L protein for co-stimulatory activation of an immune response
| Alternative Name | CD40L:ACRP30headless, CD154:ACRP30headless, TNFSF 5:ACRP30headless, gp39:ACRP30headless |
|---|---|
| Purity | ≥90% (SDS-PAGE) |
| Source | Produced in CHO cells. The extracellular domain of human CD40L (CD154) (aa 116-261) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag. |
MEGACD40L® Protein (soluble) (mouse), (recombinant)
ALX-522-120
High activity, high purity CD40L protein for co-stimulatory activation of an immune response
| Alternative Name | CD40L:ACRP30headless, CD154:ACRP30headless, TNFSF5:ACRP30headless, gp39:ACRP30headless |
|---|---|
| Purity | ≥95% (SDS-PAGE) |
| Source | Produced in CHO cells. The extracellular domain of mouse CD40L (CD154) (aa 115-260) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag. |
| Purity | ≥85% (HPLC) |
|---|---|
| Source | Isolated from bee venom. |
| CAS | 71125-38-7 |
|---|---|
| Couple Type | Inhibitor |
| Purity | ≥98% (UHPLC) |
| Alternative Name | MAFP, Methylphosphonofluoridic acid 5,8,11,14-eicosatetraenyl ester |
|---|---|
| CAS | 188404-10-6 |
| Couple Type | Inhibitor |
| Purity | ≥98% (TLC) |
MG-132
BML-PI102
A potent proteasome inhibitor that blocks protein degradation, crucial for investigating protein turnover and the ubiquitin-proteasome pathway.
| Purity | ≥98% |
|---|
| Alternative Name | (S,R)-3-(4-Hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid methyl ester, Macrophage migration inhibitory factor antagonist, ISO-1 |
|---|---|
| CAS | 478336-92-4 |
| Couple Type | Inhibitor |
| Purity | ≥97% (HPLC) |
| Alternative Name | SC-29333 |
|---|---|
| CAS | 59122-46-2 |
| Couple Type | Ligand |
| Purity | ≥99% (TLC) |
| Alternative Name | (±)-15-Deoxy-(16R,S)-16-hydroxy-16-methyl-prostaglandin E1 |
|---|---|
| CAS | 112137-89-0 |
| Couple Type | Ligand |
| Purity | ≥98% (TLC) |
| Alternative Name | L660,711 |
|---|---|
| CAS | 115104-28-4 |
| Couple Type | Ligand |
| Purity | ≥90% (HPLC) |
| Alternative Name | L-663,536, 3-[1-(p-Chlorobenzyl)-5-(isopropyl)-3-t-butylthioindol-2-yl]-2,2-dimethylpropanoic acid . Na |
|---|---|
| CAS | 118414-82-7 |
| Couple Type | Inhibitor |
| Purity | ≥98% (HPLC) |
| Alternative Name | CYT 387, N-(cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]-benzamide |
|---|---|
| CAS | 1056634-68-4 |
| Couple Type | Inhibitor |
| Purity | ≥97% (HPLC) |
| Alternative Name | MPL-A, Glucopyranosyl lipid adjuvant, GLA |
|---|---|
| CAS | 1246298-63-4 |
| Couple Type | Activator, Ligand |
Monophosphoryl Lipid A from E. coli, Serotype R515 (Re) (TLRGRADE®) (Ready-to-Use)
ALX-581-203
TLR4 activator
| Alternative Name | MPL-A from E. coli, Serotype R515 (Re) |
|---|---|
| Couple Type | Activator, Ligand |
| Purity | ≥99.9% (regarding protein or DNA contaminants; KDO not detectable) |
