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Home Small Molecule Chemistry Small Molecules - Browse by Biological Activity Antitumor Agents Page 12

Antitumor Agents

 

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16 out of 216 results

Romidepsin

ENZ-CHM468

HDAC inhibitor

Alternative Name FK-228, FR901228, Depsipeptide
CAS 128517-07-7
Couple Type Inhibitor
Purity ≥98% (HPLC)
  • ENZ-CHM468-0005   —   5 mg
    $438.00

SC-236

ALX-270-377

COX inhibitor

14 citations

Alternative Name 4-[5-(4-Chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide
CAS 170569-86-5
Couple Type Inhibitor
Purity ≥95% (HPLC)
  • ALX-270-377-M005   —   5 mg
    $149.00
  • ALX-270-377-M025   —   25 mg
    $470.00

SCREEN-WELL® Cancer Library

ENZ-LIB102

Essential standards for cancer inhibitor screening

1 citation

  • ENZ-LIB102-0100   —   1 Library
    100 µl/well

Sedanolide

ALX-350-229

GST activator

4 citations

Alternative Name 3-Butyl-3a,4,5,6-tetrahydro-1(3H)-isobenzofuranone
CAS 6415-59-4
Couple Type Activator
Purity ≥98% (UHPLC)
  • ALX-350-229-M100   —   100 mg
    $221.00

Selumetinib

ENZ-CHM184

Potent and selective ATP non-competitive inhibitor of MEK1/2

1 citation

Alternative Name AZD-6244, ARRY-142886
CAS 606143-52-6
Couple Type Inhibitor
Purity ≥95% (HPLC)
  • ENZ-CHM184-0050   —   50 mg
    $148.00

Sertraline . HCl

BML-NS115

Serotonin transporter inhibitor

1 citation

Alternative Name CP-51974
CAS 79559-97-0
Couple Type Inhibitor
Purity ≥98% (HPLC)
  • BML-NS115-0010   —   10 mg
    $97.00

SH-5

ALX-270-349

Akt inhibitor

7 citations

Alternative Name D-3-Deoxy-2-O-methyl-myo-inositol 1-[(R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate]
Couple Type Inhibitor
Purity ≥98% (TLC)
  • ALX-270-349-MC05   —   0.5 mg
    $217.00
  • ALX-270-349-M001   —   1 mg
    $368.00

Simvastatin

BML-G244

HMG-CoA reductase inhibitor

15 citations

CAS 79902-63-9
Couple Type Inhibitor
Purity ≥98% (TLC)
  • BML-G244-0050   —   50 mg
    $175.00
  • BML-G244-0250   —   250 mg
    $741.00

Simvastatin . sodium salt

ENZ-CHM142

Competitive inhibitor of HMG-CoA reductase. Suppresses TNF-induced NF-κB activation.

Alternative Name (βR,​δR,​1S,​2S,​6R,​8S,​8aR)-​8-​(2,​2-​dimethyl-​1-​oxobutoxy)-​1,​2,​6,​7,​8,​8a-​hexahydro-​β,​δ-​dihydroxy-​2,​6-​dimethyl-​1-​naphthaleneheptanoic acid .​ monosodium salt
CAS 101314-97-0
Couple Type Inhibitor
Purity ≥97% (HPLC)
  • ENZ-CHM142-0005   —   5 mg
    $162.00
  • ENZ-CHM142-0010   —   10 mg
    $299.00

SKL2001

ENZ-CHM452

Wnt/β-Catenin pathway activator

Alternative Name 5-(Furan-2-yl)-N-(3-imidazol-1-ylpropyl)-1,2-oxazole-3-carboxamide
CAS 909089-13-0
Couple Type Activator
Purity ≥98% (HPLC)
  • ENZ-CHM452-0025   —   25 mg
    $351.00

SMI-4a

ALX-270-515

Pim1 inhibitor

5 citations

CAS 327033-36-3
Couple Type Inhibitor
Purity ≥95% (HPLC, TLC, NMR/ELSD)
  • ALX-270-515-M005   —   5 mg
    $132.00

Streptozotocin

ALX-380-010

O-GlcNAcase inhibitor

41 citations

Alternative Name Streptozocin, 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose, STZ
CAS 18883-66-4
Couple Type Inhibitor
Purity ≥97% (HPLC)
  • ALX-380-010-5100   —   5x100 mg
    $169.00
  • ALX-380-010-G001   —   1 g
    $186.00

SU 9516

ALX-270-400

CDK/cyclin inhibitor

4 citations

Alternative Name 3-[1-(3H-Imidazol-4-yl)-meth-(Z)-ylidene]-5-methoxy-1,3-dihydro-indol-2-one
CAS 377090-84-1
Couple Type Inhibitor
Purity ≥95% (HPLC)
  • ALX-270-400-M005   —   5 mg
    $155.00

SU-5402

ENZ-CHM344

VEGFR2, FGFR1, and PDGFRβ inhibitor

Alternative Name 3-[4-Methyl-2-(2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-1H-pyrrol-3-yl]-propionic acid
CAS 215543-92-3
Couple Type Inhibitor
Purity ≥98% (HPLC)
  • ENZ-CHM344-0025   —   25 mg
    $347.00

Sulindac sulfide

BML-AP200

COX inhibitor

6 citations

Alternative Name Z-5-Fluoro-2-methyl-1-[p-(methylthio)benzylidene]indene-3-acetic acid
CAS 32004-67-4
Couple Type Inhibitor
Purity ≥99% (TLC)
  • BML-AP200-0005   —   5 mg
    $91.00
  • BML-AP200-0025   —   25 mg
    $286.00

Sulindac sulfone

BML-AP201

Sulindac metabolite

2 citations

Alternative Name Z-5-Fluoro-2-methyl-1-[p-(methyl-sulfonyl)benzylidene]indene-3-acetic acid
CAS 59864-04-9
Purity ≥94% (HPLC)
  • BML-AP201-0005   —   5 mg
    $93.00
  • BML-AP201-0025   —   25 mg
    $286.00

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