PCI-34051 is a potent and selective HDAC8 inhibitor with greater than 200-fold selectivity over HDACs 1, 2, 3, 6, 10. Unlike broad-spectrum HDAC inhibitors, it does not cause detectable histone or tubulin acetylation. It is a very useful tool for exploring the role of HDAC8 in cellular function.
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Regulatory Status |
RUO – Research Use Only |
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