NAD+ (SIRT Substrate)

BML-KI282

9 citations

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Product Details

Couple Target	SIRT
Couple Type	Substrate
Formulation	50mM Nicotinamide adenine dinucleotide (oxidized form) in 50mM Tris/HCl, pH 8.0, containing 137mM sodium chloride, 2.7mM KCl and 1mM MgCl₂.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-80°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

T-type voltage-gated channels, Na+/Ca2+-exchanger, and calpain-2 promote photoreceptor cell death in inherited retinal degeneration: Yan, J., Wang, L., et al.; Cell Commun. Signal. 22, 92 (2024), Abstract
HDAC inhibition delays photoreceptor loss in Pde6b mutant mice of retinitis pigmentosa: insights from scRNA-seq and CUT&Tag: Dong, Y., Yan, J., et al.; PeerJ 11, e15659 (2023), Abstract
Inherited Retinal Degeneration: Towards the Development of a Combination Therapy Targeting Histone Deacetylase, Poly (ADP-Ribose) Polymerase, and Calpain: Dong, Y., Yan, J., et al.; Biomolecules 13, (2023), Abstract
Inherited retinal degeneration: T-type voltage-gated channels, Na+/Ca2+-exchanger and calpain-2 promote photoreceptor cell death: Yan, J., Wang, L., et al.; bioRxiv , (2023)
PARP1 associates with R-loops to promote their resolution and genome stability: Laspata, N., Kaur, P., et al.; Nucleic Acids Res. 51, 2215 (2023), Abstract
Two Novel Proline-Containing Catechin Glucoside from Water-Soluble Extract of Codonopsis pilosula: F.Y. Qin, et al.; Molecules 23, E180 (2018), Application(s):SIRT1 Inhibition, Abstract — Full Text
A Novel Flavonoid Glucoside from the Fruits of Lycium ruthenicun: J.J. Qi, et al.; Molecules 23, E325 (2018), Abstract — Full Text
Design, synthesis of allosteric peptide activator for human SIRT1 and its biological evaluation in cellular model of Alzheimer’s disease: R. Kuma, et al.; Eur. J. Med. Chem. 127, 909 (2017), Abstract
Identification of the Binding Site of Chroman-4-one-Based Sirtuin 2-Selective Inhibitors using Photoaffinity Labeling in Combination with Tandem Mass Spectrometry: T. Seifert, et al; J. Med. Chem. 59, 10794 (2016), Abstract

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