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Malondialdehyde polyclonal antibody

ALX-210-879

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MDA (Malondialdehyde) is a highly reactive three carbon dialdehyde produced as a byproduct of polyunsaturated fatty acid peroxidation and arachidonic acid metabolism. MDA readily combines with several functional groups on molecules including proteins, lipoproteins, and DNA. MDA modified proteins may show altered physico-chemical behavior and antigenicity. Antibodies to MDA will help to visualize the MDA-adducts.

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This antibody is covered by our Worry-Free Guarantee.

Product Details

Alternative Name	MDA
Application	ELISA, IHC, WB
Formulation	Liquid. Contains 0.1% sodium azide.
Host	Rabbit
Immunogen	Malondialdehyde (MDA) conjugated to KLH.
Purity Detail	Unpurified
Recommendation Dilutions/Conditions	ELISA (1:1,000-1:10,000)Immunohistochemistry (1:500-1:1,000)Western blot (1:500-1:1,000)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.
Species Reactivity	Species independent
Specificity	Recognizes MDA adducts.
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Handling & Storage

Use/Stability	Do not freeze, thaw or store diluted working solutions.
Handling	Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Aged Mice Devoid of the M3 Muscarinic Acetylcholine Receptor Develop Mild Dry Eye Disease.: Li, H., Xia, N., et al.; Int. J. Mol. Sci. 22, (2021), Reactant(s): Mouse, Abstract
Upregulation of Carbonyl Reductase 1 by Nrf2 as a Potential Therapeutic Intervention for Ischemia/ Reperfusion Injury during Liver Transplantation.: Tak, E., Kim, N., et al.; Mol. Cells 42, 672 (2019), Application(s): WB / Reactant(s): Human, Abstract
Epigallocatechin-3-gallate protects against hepatic ischaemia-reperfusion injury by reducing oxidative stress and apoptotic cell death: E. Tak, et al.; J. Int. Med. Res. 44, 1248 (2016), Application(s): Western blot / Reactant(s): Mouse, Abstract — Full Text
Glomerular malondialdehyde levels in patients with focal and segmental glomerulosclerosis and minimal change disease: S.T. Nezhad, et al.; Saudi J. Kidney Dis.Transpl. 21, 886 (2010), Abstract — Full Text
Astrocyte-targeted expression of IL-6 protects the CNS against a focal brain injury.: M. Penkowa, et al.; Exp. Neurol. 181, 130 (2003), Abstract
Role of metallothionein-III following central nervous system damage.: J. Carrasco, et al.; Neurobiol. Dis. 13, 22 (2003), Abstract
Altered inflammatory response and increased neurodegeneration in metallothionein I+II deficient mice during experimental autoimmune encephalomyelitis.: M. Penkowa, et al.; J. Neuroimmunol. 119, 248 (2001), Abstract
Interleukin-6 deficiency reduces the brain inflammatory response and increases oxidative stress and neurodegeneration after kainic acid-induced seizures.: M. Penkowa, et al.; Neuroscience 102, 805 (2001), Abstract
Enhanced seizures and hippocampal neurodegeneration following kainic acid-induced seizures in metallothionein-I + II-deficient mice.: J. Carrasco, et al.; Eur. J. Neurosci. 12, 2311 (2000), Abstract

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Malondialdehyde polyclonal antibody

ALX-210-879

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

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