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Synapsin II polyclonal antibody

ADI-VAS-SV061

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Synapsin I, II and III belong to a family of neuron-specific phosphoproteins which maintain a reserve pool of vesicles in the vicinity of the active zone by tethering synaptic vesicles to each other and to an Actin-based cytoskeleton meshwork. They have been shown to regulate neurotransmitter release in mature synapses and to accelerate development of the nervous system.

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This antibody is covered by our Worry-Free Guarantee.

Product Details

Alternative Name	SYN2
Application	IP, WB
Application Notes	Detects a band of ~74kDa (synapsin Iia) and ~54kDa (synapsin Iib) by Western blot.
Formulation	Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
Gene/Protein Identifier	C30411 (PIR)
Host	Rabbit
Immunogen	Synthetic peptide corresponding to a portion of rat Synapsin II. The sequence is completely conserved in mouse.
Purity Detail	Protein A affinity purified.
Recommendation Dilutions/Conditions	Immunoprecipitation (1:100)Western Blot (1µg/ml, colorimetric)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.
Source	Purified from rabbit serum.
Species Reactivity	Mouse, Rat
UniProt ID	Q63537
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Handling & Storage

Handling	Avoid freeze/thaw cycles.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Phylogenomics of the rarest animals: a second species of Micrognathozoa identified by machine learning: Sato, S., Appeldorff, C., et al.; Proc. Biol. Sci. 292, 20242867 (2025), Abstract
SIVA-1 regulates apoptosis and synaptic function by modulating XIAP interaction with the death receptor antagonist FAIM-L: E. Coccia, et al.; Cell Death Dis. 11, 82 (2020), Application(s): ICC, Abstract — Full Text
High diversity in neuropeptide immunoreactivity patterns among three closely related species of Dinophilidae (Annelida): Kerbl, A., Conzelmann, M., et al.; J. Comp. Neurol. 525, 3596 (2017), Abstract
Detailed reconstruction of the musculature in Limnognathia maerski (Micrognathozoa) and comparison with other Gnathifera: Bekkouche, N., Kristensen, R. M., et al.; Front. Zool. 11, 71 (2015), Abstract