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| Alternative Name | IL-1β converting enzyme, Interleukin-1β converting enzyme, ICE |
|---|---|
| Application | ELISA, Flow Cytometry, WB |
| Host | Rat |
| Isotype | IgG1 |
| Species Reactivity | Mouse |
| Alternative Name | 7-Allyl-8-oxoguanosine, RWJ 21757 |
|---|---|
| CAS | 121288-39-9 |
| Couple Type | Ligand |
| Purity | ≥97% (HPLC (UV)) |
| Alternative Name | FLICE |
|---|---|
| Application | IHC (FS), IP, WB |
| Host | Mouse |
| Isotype | IgG2b |
| Species Reactivity | Human |
| Alternative Name | 6-Nitro[b]thiophene-1,1-dioxide |
|---|---|
| CAS | 19983-44-9 |
| Couple Type | Inhibitor |
| Purity | ≥98% (TLC) |
| Alternative Name | CD95, APO-1, TNFRSF 6 |
|---|---|
| Application | Flow Cytometry, FUNC |
| Host | Mouse |
| Isotype | IgG3 |
| Species Reactivity | Human |
| Alternative Name | 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol . HCl, Fingolimod . HCl |
|---|---|
| CAS | 162359-56-0 |
| Couple Type | Ligand |
| Purity | ≥98% (HPLC) |
Caspase-8 (human), (recombinant)
BML-SE172
Highly active caspase-8 for the study of enzyme regulation and kinetics
| Alternative Name | FLICE, Mch5, MACH |
|---|---|
| Purity | ≥90% (SDS-PAGE) |
| Source | Produced in E. coli |
| Alternative Name | α-Cyano-(4-hydroxy)cinnamonitrile |
|---|---|
| CAS | 3785-90-8 |
| Couple Type | Inhibitor |
| Purity | ≥98% (TLC) |
| Alternative Name | Mch3, CMH-1 |
|---|---|
| Purity | ≥95% (SDS-PAGE) |
| Source | Produced in E. coli. Human caspase-7 (aa 24-303). Genbank Accession No. U40281. |
| Alternative Name | Interleukin 1β converting enzyme, IL-1β converting enzyme, ICE |
|---|---|
| Purity | ≥90% (SDS-PAGE) |
| Source | Produced in E. coli. cDNA encodes residues identical to Asn120-His404 (C-terminus) at Genbank Accession No. M87507, except for an Asp381 to Glu change, introduced to stabilize the enzyme against autoproteolysis. |
Enhancer for Ligands
ALX-804-034
Enhances biological activity of TRAIL, soluble (human) (recombinant) and FasL, soluble (human) (recombinant).
SUPERKILLERTRAIL® Protein (soluble) (human), (recombinant)
ALX-201-115
Enhanced ligand with improved stability providing significantly enhanced immune activation.
| Alternative Name | TNFSF 10, Apo-2L, CD253 |
|---|---|
| Purity | ≥98% (SDS-PAGE). MS analysis, <1% impurity (mainly Hsp70 protein from E. coli) |
| Source | Produced in E. coli. The extracellular domain of human TRAIL (aa 95-281) is fused at the N-terminus to a His-tag and a linker peptide. The active multimeric conformation is stabilized by an inserted mutation allowing an additional CC-bridge. |
| Alternative Name | C-C chemokine receptor 4, CD194 |
|---|---|
| Application | ELISA, Flow Cytometry, ICC, IHC (PS), WB |
| Host | Goat |
| Species Reactivity | Mouse |
| CAS | 13220-57-0 |
|---|---|
| Couple Type | Inhibitor |
| Purity | ≥98% (1H-NMR, HPLC) |