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| CAS | 71186-53-3 |
|---|---|
| Couple Type | Blocker |
| Purity | ≥98% (TLC) |
Cdk/Crk inhibitor
ENZ-CHM131
Potent, selective, and ATP-competitive inhibitor of Cdks. Antiproliferative.
| Alternative Name | 1-(2,6-Dichlorophenyl)-1,5-dihydro-6-((4-(2-hydroxyethoxy)phenyl)methyl)-3-(1-methylethyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one, RGB-286147, Cdk7 Inhibitor IV |
|---|---|
| CAS | 784211-09-2 |
| Couple Type | Inhibitor |
| Purity | ≥98% (HPLC) |
| Alternative Name | ATM kinase inhibitor, 2-Morpholino-6-(thianthren-1-yl)-4H-pyran-4-one |
|---|---|
| CAS | 587871-26-9 |
| Couple Type | Inhibitor |
| Purity | ≥99% (HPLC) |
mTOR inhibitor WYE-28
ENZ-CHM137
Cell-permeable, potent, selective, and ATP-competitive mTOR inhibitor.
| Alternative Name | 4-(6-{4-[3-(4-Hydroxymethyl-phenyl)-ureido]-phenyl}-4-morpholin-4-yl-pyrazolo[3,4-d]pyrimidin-1-yl)-piperidine-1-carboxylic acid methyl ester |
|---|---|
| CAS | 1062172-60-4 |
| Couple Type | Inhibitor |
| Purity | ≥97% (HPLC) |
| Alternative Name | U-10858 |
|---|---|
| CAS | 38304-91-5 |
| Couple Type | Activator |
| Purity | ≥98% (HPLC) |
mTOR inhibitor WYE-132
ENZ-CHM140
Highly potent, ATP-competitive, and specific mTOR kinase inhibitor. Antiproliferative.
| Alternative Name | 1-{4-[1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-4-(8-oxa-3-aza-bicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]-phenyl}-3-methyl-urea, WYE-125132 |
|---|---|
| CAS | 1144068-46-1 |
| Couple Type | Inhibitor |
| Purity | ≥99% (HPLC) |
| Alternative Name | Probable global transcription activator SNF2L1, SMARCA1, SMCA1 |
|---|---|
| Source | Produced in insect (Sf9) cells. Human SNF2L (aa 2-1054) fused to a FLAG-tag at the N-terminus. |
| Alternative Name | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1, DAAD, Marcal1, SMAL1, SMARCAL1 |
|---|---|
| Source | Produced in insect (Sf9) cells. Human HARP (aa 2-953) fused to 6xHis and FLAG-tag at the N-terminus. |
| Alternative Name | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5, SMARCA5, SMCA5, WCRF135 |
|---|---|
| Source | Produced in insect (Sf9) cells. Human SNF2H (aa 2-1052) fused to a FLAG-tag at the N-terminus. |
| Alternative Name | KDR, FLK-1, Vascular endothelial growth factor receptor 2 |
|---|---|
| Purity | ≥90% (SDS-PAGE) |
| Source | Produced in Sf9 insect cells with N-terminal GST tage. Human VEGFR2 (aa 805-1356). Produced in a baculovirus expression system. |
| Alternative Name | Helicase SRCAP, DOMO1, DOMH2, EAF1, FLHS, KIAA0309, SWR1 |
|---|---|
| Source | Produced in insect (Sf9) cells. Human SRCAP (aa 2-3070) fused to 6xHis and FLAG-tag at the N-terminus. |
| Alternative Name | Chaperonin 60, CPN60, HspD1, Heat shock protein 60 |
|---|---|
| Purity | ≥90% (SDS-PAGE; Western blot) |
| Source | Produced in E. coli. |
| Alternative Name | (5-Methyl-1H-pyrazol-3-yl)-(2-phenylquinazolin-4-yl)amine |
|---|---|
| CAS | 404828-08-6 |
| Couple Type | Inhibitor |
| Purity | ≥99% (HPLC) |
| Alternative Name | Heat shock protein 40, DnaJ protein homolog 1 |
|---|---|
| Purity | ≥80% (SDS-PAGE) |
| Source | Produced in E. coli. Contains N-terminal His tag. |
| Alternative Name | Proteasome subunit α type-1, -2, -3, -4, -5 & -6, Macropain subunits C2, C3, C8, C9, ι & ζ |
|---|---|
| Application | IHC, WB |
| Host | Mouse |
| Isotype | IgG1κ |
| Species Reactivity | Human, Mouse, Potato, Rabbit, Rat, Yeast |