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β-Lapachone

BML-GR308

3 citations

  • BML-GR308-0005   —   5 mg
    $99.00
  • BML-GR308-0025   —   25 mg
    $421.00

Novel DNA topoisomerase I inhibitor. Unlike camptothecin, β-lapachone does not stabilize the cleavable complex, indicating a novel mode of action. Induces apoptosis in HL-60 and human prostate cancer cells via a p53-independent mechanism and blocks the cell cycle at G0/G1.

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Regulatory Status

RUO – Research Use Only