Selective estrogen receptor ERβ agonist displaying 68-fold greater selectivity over ERα (EC50 = 2 and 155nM, respectively). It stimulates galanin expression in GnRH neurons and displays anxiolytic/antidepressant activity in various in vivo rodent models (administration to mice at 30mg/kg s.c.).
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Regulatory Status |
RUO – Research Use Only |
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