PINK1 polyclonal antibody

The anti-PINK1 antibody is a highly specific and sensitive tool for detecting human PINK1 in tissue and cell samples, optimized for immunohistochemistry (IHC) and immunofluorescence (IF) applications to study mitochondrial quality control and neurodegenerative pathways.

PINK1 is a mitochondrial kinase essential for maintaining mitochondrial quality control and promoting cell survival under stress conditions. It plays a critical role in protecting neurons from oxidative stress-induced cell death by maintaining mitochondrial integrity. Deficiency in PINK1 leads to mitochondrial dysfunction, elevated oxidative stress, and subsequent neuronal degeneration.