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Regulatory Status |
RUO – Research Use Only |
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TLR4 activator
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Activity |
Specific activator of Toll-like receptor (TLR) 4. Does not activate TLR2 or other TLRs as determined with splenocytes and macrophages from TLR4 deficient mice. Smooth (S)-form LPS are commonly the preferred choice for whole animal studies, whereas Rough (R)-form LPS are primarily used in cellular in vitro activation studies. |
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Alternative Name |
Lipopolysaccharide from Salmonella typhimurium S-form |
Couple Target |
TLR, TLR4 |
Couple Type |
Activator, Ligand |
Formulation |
Liquid. Sterile, ready-to-use solution in pyrogen-free double distilled water. |
Purity |
Absence of detectable protein or DNA contaminants with agonistic TLR activity. |
Source |
Smooth (S)-form LPS, isolated and purified from Salmonella typhimurium (wild type) by the hot phenol-water method and dissolved in sterile pyrogen-free double distilled water. |
Use/Stability |
As indicated on product label or CoA when stored as recommended. Stable for at least 1 year after receipt when stored at +4°C. |
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Handling |
Do not ingest. Wear gloves and mask when handling this product! Avoid contact through all modes of exposure. LPS compounds are highly pyrogenic. Avoid accidental injection; extreme care should be taken when handling in conjunction with hypodermic syringes. Use must be restricted to qualified personnel. |
Long Term Storage |
+4°C |
Shipping |
Ambient Temperature |
Regulatory Status |
RUO – Research Use Only |
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Alternative Name | D-Bicuculline |
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CAS | 485-49-4 |
Couple Type | Inhibitor, Ligand |
Purity | ≥98% (HPLC) |
Alternative Name | (±)-Anatoxin A fumarate, (±)-2-Acetyl-9-aza bicyclo[4,2,1]non-2-ene fumarate |
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CAS | 1219922-30-1 |
Couple Type | Ligand |
Purity | ≥96% (HPLC) |
CAS | 69906-85-0 |
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Couple Type | Ligand |
Purity | ≥99% (TLC) |
CAS | 40709-69-1 |
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Couple Type | Ligand |
Purity | ≥98% (HPLC) |
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