INSM1 monoclonal antibody (A-8)

INSM1 (A-8) Mouse Monoclonal Antibody is intended for qualitative immunohistochemistry with normal and neoplastic formalin-fixed, paraffin-embedded tissue sections, to be viewed by light microscopy. 

INSM1 (Insulinoma-associated protein 1) is a transcription factor primarily known for its role in neuroendocrine differentiation and development. It is expressed in various neuroendocrine tissues and tumors, including pancreatic neuroendocrine tumors (NETs), neuroendocrine lung tumors, and neuroendocrine carcinomas of the gastrointestinal tract. INSM1 plays a crucial role in regulating the expression of genes involved in neuroendocrine cell fate determination, differentiation, and hormone production. Its expression pattern and potential diagnostic and prognostic significance make it a valuable biomarker in neuroendocrine tumor pathology and research.