Cytochrome P-450 2D4 (CYP2D4; also known as debrisoquine-4-hydroxylase), is found at very low levels in normal rat brain, but administration of clozapine (Prod. No. BML-D107) induces high levels in many areas including the substantia nigra pars compacta, ventral tegmental area, in the olfactory bulb and in granule and Purkinje cells in the cerebellum.
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Regulatory Status |
RUO – Research Use Only |
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