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Busulfan

ALX-400-048

4 citations

  • ALX-400-048-G010   —   10 g
    $60.00

Antineoplastic bifunctional, DNA alkylating agent that causes DNA damage by cross-linking DNA and proteins. Causes double-base lesions mainly at 5’-GA-3’ and, to a lesser extent, at 5’-GG-3’ sequences. Forms an intrastrand cross-link at the 5’-GA-3’ sequence, in addition to monoalkylation. Selectively induces normal human fibroblast senescence through Erk and p38 pathways.

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Regulatory Status

RUO – Research Use Only