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Bcl-w monoclonal antibody (13F9)

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Alternative Name	BCL2L2
Application	IP, WB
Application Notes	Excellent for Immunoprecipitation.
Clone	13F9
Formulation	Liquid. In PBS containing 0.02% sodium azide.
Host	Rat
Immunogen	Recombinant human Bcl-w.
Isotype	IgG2a
Purity Detail	Protein G-affinity purified.
Species Reactivity	Dog, Human, Monkey, Mouse, Rat
UniProt ID	Q92843
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Regulatory Status	RUO – Research Use Only

Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic: J. Kuroda, et al.; PNAS 103, 14907 (2006), Abstract — Full Text
Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity: J. Wilson-Annan, et al.; J. Cell Biol. 162, 877 (2003), Abstract — Full Text
Tissue expression and subcellular localization of the pro-survival molecule Bcl-w: L.A. O’Reilly, et al.; Cell Death Differ. 8, 486 (2001), Abstract
Bcl-w is an important determinant of damage-induced apoptosis in epithelia of small and large intestine: D.M. Pritchard, et al.; Oncogene 19, 3955 (2000), Abstract

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