Home Shop 1-O-Hexadecyl-2-O-acetyl-sn-glycero-3-phosphorylcholine

1-O-Hexadecyl-2-O-acetyl-sn-glycero-3-phosphorylcholine

BML-L100

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PAF receptor ligand

Platelet activating factor (PAF) with a C₁₆ alkyl group. Initiates receptor-mediated responses in platelets and a variety of other cells. Rabbit platelet PAF receptor K_D=0.1 nM. EC₅₀ for stimulation of phosphoinositide metabolism in hippocampal cell line: 1.2-1.5 nM.

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Product Details

Alternative Name	PAF C-16
Appearance	White solid.
CAS	74389-68-7
Couple Target	PAF receptor
Couple Type	Ligand
Formula	C₂₆H₅₄NO₇P
MI	14: 7524
MW	523.7
Purity	≥98% (TLC)
Solubility	Soluble in 100% ethanol (>100 mg/ml). Soluble in water (>100mg/ml) after sonication for 1 minute at 40°C.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended. Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 2 months at -20°C.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Biotinylated heptapeptides substituted with a d-amino acid as platelet-activating factor inhibitors: A. Sato, et al.; Eur. J. Pharmacol. 764, 202 (2015), Application(s): Injection into rat hind paw, Spectroscopy, Abstract
Blood cardiolipin in haemodialysis patients. Its implication in the biological action of platelet-activating factor: S. Antonopoulou, et al.; Int. J. Biochem. Cell Biol. 28, 43 (1996), Abstract
Guanine nucleotide regulatory proteins, Gq and Gi1/2, mediate platelet-activating factor-stimulated phosphoinositide metabolism in immortalized hippocampal cells: L.C. Shi, et al.; J. Neurochem. 67, 1478 (1996), Abstract

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1-O-Hexadecyl-2-O-acetyl-sn-glycero-3-phosphorylcholine

BML-L100

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

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