Key to producing cost-effective and efficient biopharmaceuticals
Improving bioprocesses is essential to maximizing yield in the production of biopharmaceuticals. This involves optimizing various stages of the production process, such as improving the cell culture conditions, enhancing the purification process, developing better bioreactors, and implementing process analytical technology (PAT) for real-time monitoring and control. By continually improving bioprocesses, the biopharmaceutical industry can increase yield, reduce production costs, and ultimately provide more patients with access to life-saving medications.
Upstream Bioprocess
Cell Culture & Process Optimization
Maximizing yield in biopharmaceutical production is crucial for optimizing productivity and cost-effectiveness. It involves strategic process optimization, such as enhancing cell culture conditions, optimizing fermentation parameters, and improving downstream purification techniques.
MEGACD40L® Protein (soluble)(human) (recombinant)
Achieve rapid expansion of primary B cells with MEGACD40L® recombinant protein. Using MEGACD40L® in association with other stimulants can improve expansion of primary B cells by 36 fold, based on the work by Hung KL, et alz
B cell lymphocyte activation by various CD40L constructs. PBMCs were treated for 48 hrs in media containing serially diluted CD40L, CD40L + 2 μg/mL Enhancer, or MEGACD40L® Protein.
Small Molecules and Peptides
Incorporating small molecules into bioprocessing workflows can enhance productivity at various stages of the production cycle. These molecules act as potent enhancers, catalysts, or modulators, driving improvements in yield, quality, and overall process performance.
Our chemistry and compound range includes over 3,000 stand-alone small molecules with known activity, including natural products, enzyme inhibitors, receptor ligands, drugs, lipids, and fatty acids. From metabolic engineering to downstream processing, these compounds offer unprecedented opportunities to enhance productivity, streamline workflows, and achieve greater efficiency in producing valuable biologics.
AMPIVIEW® RNA probes
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