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Cell Signaling
| Alternative Name | CYT 387, N-(cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]-benzamide |
|---|---|
| CAS | 1056634-68-4 |
| Couple Type | Inhibitor |
| Purity | ≥97% (HPLC) |
| Alternative Name | MPL-A, Glucopyranosyl lipid adjuvant, GLA |
|---|---|
| CAS | 1246298-63-4 |
| Couple Type | Activator, Ligand |
Monophosphoryl Lipid A from E. coli, Serotype R515 (Re) (TLRGRADE®) (Ready-to-Use)
ALX-581-203
TLR4 activator
| Alternative Name | MPL-A from E. coli, Serotype R515 (Re) |
|---|---|
| Couple Type | Activator, Ligand |
| Purity | ≥99.9% (regarding protein or DNA contaminants; KDO not detectable) |
Monophosphoryl Lipid A from Salmonella minnesota R595 (Re) (TLRGRADE®) (Ready-to-Use)
ALX-581-202
TLR4 activator
| Alternative Name | MPL-A from Salmonella minnesota R595 (Re) |
|---|---|
| Couple Type | Activator, Ligand |
| Purity | ≥99.9% (regarding protein or DNA contaminants; KDO not detectable) |
| Alternative Name | MSU (crystals), Uric Acid (crystals) |
|---|---|
| CAS | 1198-77-2 |
| Couple Type | Activator |
| Alternative Name | AMG-706 |
|---|---|
| CAS | 453562-69-1 |
| Couple Type | Inhibitor |
| Purity | ≥99% (HPLC) |
| Alternative Name | 6-Methyl-2-(phenylethynyl)-pyridine . HCl |
|---|---|
| CAS | 96206-92-7 |
| Couple Type | Inhibitor, Ligand |
| Purity | ≥99% |
| Alternative Name | CD206, Macrophage mannose receptor 1, MMR |
|---|---|
| Purity | ≥95% (SDS-PAGE) |
| Source | Produced in HEK293 cells. A DNA sequence encoding the human MRC1 (Leu19-Ser1386) was expressed with a polyhistidine tag at the C-terminus. |
| Alternative Name | N-[2-(3,4-Dimethylbenzyl)-3-(pivalyloxy)propyl]-2-[4-(2-aminoethoxy)-3-methoxyphenyl]acetamide |
|---|---|
| CAS | 289902-82-5 |
| Couple Type | Activator |
| Purity | ≥98% |
| CAS | 329205-68-7 |
|---|---|
| Couple Type | Inhibitor, Ligand |
| Purity | ≥98% (HPLC) |
| Alternative Name | Mortalin, Heat shock protein 70 (mitochondrial), GRP75 |
|---|---|
| Application | ICC, IP, WB |
| Host | Mouse |
| Isotype | IgG3 |
| Species Reactivity | Dog, Human, Monkey, Mouse |
| Alternative Name | mTOR (human FKBP12-rapamycin-binding domain) |
|---|---|
| Application | ChIP, ICC, WB |
| Host | Rabbit |
| Species Reactivity | Human |
mTOR inhibitor WYE-132
ENZ-CHM140
Highly potent, ATP-competitive, and specific mTOR kinase inhibitor. Antiproliferative.
| Alternative Name | 1-{4-[1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-4-(8-oxa-3-aza-bicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]-phenyl}-3-methyl-urea, WYE-125132 |
|---|---|
| CAS | 1144068-46-1 |
| Couple Type | Inhibitor |
| Purity | ≥99% (HPLC) |
mTOR inhibitor WYE-23
ENZ-CHM136
Cell-permeable, potent, selective, and ATP-competitive mTOR inhibitor.
| Alternative Name | 4-{6-[4-(3-Cyclopropyl-ureido)-phenyl]-4-morpholin-4-yl-pyrazolo[3,4-d]pyrimidin-1-yl}-piperidine-1-carboxylic acid methyl ester |
|---|---|
| CAS | 1062169-46-3 |
| Couple Type | Inhibitor |
| Purity | ≥99% (HPLC) |
mTOR inhibitor WYE-28
ENZ-CHM137
Cell-permeable, potent, selective, and ATP-competitive mTOR inhibitor.
| Alternative Name | 4-(6-{4-[3-(4-Hydroxymethyl-phenyl)-ureido]-phenyl}-4-morpholin-4-yl-pyrazolo[3,4-d]pyrimidin-1-yl)-piperidine-1-carboxylic acid methyl ester |
|---|---|
| CAS | 1062172-60-4 |
| Couple Type | Inhibitor |
| Purity | ≥97% (HPLC) |
