Immuno-Oncology

Trusted Immuno-Oncology Research Tools - Backed by Thousands of Citations


Recombinant Proteins

PD-1
PD-L1
OX40
OX40L

Immune Checkpoints

LAG-3
CTLA-4
TIM-3
PD-1
PD-L1

B Cell Activation

MEGACD40L® Protein

Inflammatory Cytokines and Chemokines

IFN-γ
CCL2
IL-8
IL-6
IL-1β


Immunogenic Cell Death


Highly specific antibodies validated for various applications, from flow cytometry to IHC, to help you discover immune checkpoint inhibitors, develop novel immunotherapies, and support your immuno-oncology research.

LAG-3 (human) monoclonal antibody

PD-L1 monoclonal antibody


High-Specificity ELISAs for Innate and Adaptive Immune Research

Enzo offers a large variety of immunoassay kits in both immunometric and competitive assay formats. As scientists and manufacturers of kits, we understand the critical nature of your research. Each kit is put through rigorous testing to ensure high precision, accuracy, sensitivity, and specificity. You can be confident that you will obtain reproducible results, day-after-day, and lot-after-lot.

  • Sensitivity – detect even the lowest sample concentration
  • Broad Range – minimize need for dilution
  • Consistent – strict quality control guidelines ensure reproducible results, lot-after-lot
  • Trusted – reliability highlighted in peer-reviewed publications for three decades
  • Flexible – wide range of sample types
Highly Sensitive Measurement of IL-6

A typical standard curve for IL-6 (human) High Sensitivity ELISA kit

Cytokine & Interleukin ELISAs

HumanHumanMouse
AdiponectinIL-13IFN-γ
CD40IL-33IL-1β
CD40LLeptinIL-2
FasLNamptIL-6
IFN-γOsteoprotegerinLeptin
IGF-1RANKLLipocalin 2 (NGAL)
IL-1βLipocalin 2 (NGAL)Nampt
IL2TNF-αTGF-β1
IL-4TNF-R1TNF-α
IL-6TGF-β1
IL8
IL-10

Key Toll-like Receptor Ligands

TLRs play a role in the innate immune system, detecting pathogen-associated molecule patterns (PAMPs) of bacterial, viral, fungal, and protozoal origin.


Co-Stimulation of T Cell Response

Superior Performance from Carefully Engineered TNF Superfamily Ligands MEGACD40L® Protein (soluble) (human), (recombinant)

TLRs play a role in the innate immune system, detecting pathogen-associated molecule patterns (PAMPs) of bacterial, viral, fungal, and protozoal origin.

  • Superior Performance from Carefully Engineered TNF Superfamily Ligands
  • MEGACD40L® Protein (soluble) (human), (recombinant)

B cell lymphocyte activation by various CD40L constructs. PBMCs were treated for 48 hrs in media containing serially diluted CD40L, CD40L + 2 μg/mL Enhancer, or MEGACD40L® Protein. Cells were dual-stained with α-human CD19–PE and α-human CD86–APC and analyzed by flow cytometry.
Data are presented as the percent of CD19+ B cells that co-stain as CD86+.


Death Receptor Ligands

Members of the tumor necrosis factor (TNF) receptor gene superfamily bind to extrinsic ligands and transduce intracellular signals leading to the destruction of the cell. Ligands, such as FasL and TNF-α, hold potential as targets for therapeutic and diagnostic applications.

SUPERFASLIGAND® Protein (soluble)(human), (recombinant)
  • Features an N-Terminus linker shown to improve stability
  • Enhanced immune activation compared to other recombinant ligands
  • Mimics glycosylation of native human FasL
Induction of Cell Death with SUPERFASLIGAND® Protein

Jurkat cells were incubated with the indicated concentration of SuperFasL and cell proliferation was assayed. % Viability was determined in comparison to control wells with no SuperFasL.


Detect Specific Cell Populations with Antibodies for CD Markers

Enzo offers over 50 CD antibodies validated for flow cytometry and microscopy applications.

CD markerT CellsB CellsDentritic CellsNK CellsStem cell precursorsmacrophagesgranulocytesendothelial cellsepithelial cells
CD3Find
CD4FindFindFind
CD8FindFind
CD9FindFindFindFindFindFind
CD11aFindFindFindFindFind
CD18FindFindFindFindFindFind
CD20FindFind
CD23FindFindFindFindFindFind
CD26FindFindFindFindFind
CD28Find
CD31FindFindFindFindFindFind
CD36FindFindFindFind
CD38FindFindFindFindFindFind
CD39FindFindFindFindFindFindFind
CD40FindFindFindFindFindFindFindFind
CD40LFind
CD41Find
CD41aFind
CD41bFind
CD42Find
CD44FindFindFindFindFindFindFind
CD45FindFindFindFindFindFindFind
CD45RAFindFindFindFindFindFind
CD49b / CD29FindFindFindFindFindFindFindFindFind
CD49fFindFindFindFindFind
CD51FindFind
CD52FindFindFindFind
CD54FindFindFindFind
CD66aFindFind
CD66bFind
CD66cFindFind
CD66eFind
CD68FindFindFindFindFindFind
CD74FindFindFindFindFindFind
CD80FindFindFindFind
CD83FindFind
CD87FindFindFindFindFind
CD107bFindFindFind
CD123FindFindFindFind
CD127FindFindFind
CD134Find
CD137FindFindFind
CD163Find
CD194FindFindFindFindFind
CD205FindFindFind
CD207Find
CD208Find
CD223FindFindFind
CD243Find
CD279Find
CD324 (E-cadherin)FindFind
CD325Find

Immuno-Oncology

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