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Human β-NGF is responsible for survival, differentiation and maturation of sympathetic and sensory neurons.
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Figure 1: Murine b-NGF induced proliferation of TF-1 cells. Serial dilutions of Mouse β-NGF, starting at 100 ng/mL, were added to TF-1 cells growing in GM-CSF free media. Cell proliferation can be measured and the linear portion of the curve can be used to calculate the ED50.
| Regulatory Status |
RUO – Research Use Only |
|---|
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| Alternative Name | β-NGF |
|---|---|
| Purity | ≥98% (HPLC) |
| Source | Produced in E. coli. Dimer of two identical subunits (119 aa) linked together by very strong hydrophobic interactions. |