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β-Amyloid (1-40)

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Appearance	White to off-white powder.
CAS	131438-79-4
Formula	C₁₉₄H₂₉₅N₅₃O₅₈S
MW	4329.9
Purity	≥95%
Quantity	*Sold as net peptide weight.
Sequence	H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH
Solubility	Soluble in 5% acetic acid.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Structure of amyloid A4-(1-40)-peptide of Alzheimer’s disease: H. Sticht, et al.; Eur. J. Biochem. 233, 293 (1995), Abstract
The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer’s disease: J.T. Jarrett, et al.; Biochemistry 32, 4693 (1993), Abstract
Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides: B.A. Yankner, et al.; Science 250, 279 (1990), Abstract

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