ZytoMation® MYC Dual Color Break Apart FISH Probe

The ZytoMation^® MYC Dual Color Break Apart FISH Probe is designed to detect translocations involving the chromosomal region 8q24.21 harboring the MYC gene. Translocations involving the MYC gene are considered cytogenetic hallmarks for Burkitt lymphoma but are also found in other types of lymphomas. The most frequent translocation involving the MYC gene region is t(8;14)(q24.21;q32.3) juxtaposing the MYC gene in 8q24.21 next to the IGH (immunoglobulin heavy chain locus) gene in 14q32.33.