ZytoLight® SPEC PDGFRB Dual Color Break Apart Probe

The ZytoLight ® SPEC PDGFRB Dual Color Break Apart Probe is designed to detect translocations involving the chromosomal region 5q32 harboring the PDGFRB gene. Translocations involving the PDGFRB gene are rare genetic disorders and are identified in myelodysplastic/myeloproliferative neoplasms, chronic myeloproliferative disorders, acute myeloid leukemia, and also in atypical chronic myeloid leukemia/chronic myelomonocytic leukemia-like diseases, often with eosinophilia and splenomegaly.