ZytoLight® SPEC DDIT3 Dual Color Break Apart Probe
ZTV-Z-2100
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The ZytoLight ® SPEC DDIT3 Dual Color Break Apart Probe is designed to detect translocations involving the chromosomal region 12q13.3 harboring the DDIT3 gene. DDIT3 is consistently rearranged in myxoid liposarcomas. The FUS-DDIT3 fusion protein acts as an abnormal transcription factor and development of myxoid liposarcomas is thus regarded as a consequence of deregulated FUS-DDIT3 target genes.
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Regulatory Status |
RUO – Research Use Only |
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