ZytoDot® SPEC ERBB2 Probe (Digoxigenin)

The ZytoDot ® SPEC ERBB2 Probe is designed for the detection of ERBB2 gene amplification, frequently observed in solid malignant neoplasms, in tissue sections or cell samples. Amplification of the proto-oncogene ERBB2, observed in approximately 20% of all breast cancer samples, has been correlated with a poor prognosis of the disease. Similar results have been obtained for a variety of other malignant neoplasms e.g. ovarian cancer, stomach cancer, and carcinomas of the salivary gland.