ZytoDot® 2C SPEC ERG Break Apart Probe

The ZytoDot ® 2C SPEC ERG Break Apart Probe is designed to detect aberrations involving the ERG gene at 21q22.2 frequently found in prostate cancers. ERG rearrangements have been observed in 40-60% of prostate cancers identified via prostate-specific antigen screening. The most common aberration affecting ERG is the interstitial deletion of about 3 Mb at the chromosomal region 21q22 found in 90% of the cases.