ZytoDot® 2C SPEC ERBB2/CEN 17 Probe (Digoxigenin/DNP)
ZTV-C-3032
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For the detection of the human ERBB2 gene and alpha-satellites of chromosome 17 by chromogenic in situ hybridization (CISH).
The ZytoDot 2C SPEC ERBB2/CEN 17 Probe is designed for the detection of ERBB2 (a.k.a HER2) gene amplification frequently observed in solid malignant neoplasms e.g. breast cancer samples. Amplification of the proto-oncogene ERBB2, observed in approximately 20% of all breast cancer samples, has been correlated with a poor prognosis of the disease.
In addition, detection of ERBB2 amplification by CISH may help in selecting patients eligible for ERBB2-targeted therapy.
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Regulatory Status |
RUO – Research Use Only |
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