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ZM-306416

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VEGFR inhibitor

VEGF receptor tyrosine kinase inhibitor. Inhibits KDR (IC₅₀=100nM) and Flt (IC₅₀=2µM) tyrosine kinases.

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Appearance	Off-white solid.
CAS	690206-97-4
Couple Target	VEGFR
Couple Type	Inhibitor
Formula	C₁₆H₁₃ClFN₃O₂
MW	333.7
Purity	≥98% (TLC)
Solubility	Soluble in DMSO (3 mg/ml) or ethanol (1 mg/ml).

Use/Stability	As indicated on product label or CoA when stored as recommended. Store, as supplied, at room temperature for up to 1 year.
Long Term Storage	Ambient
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Design and structure-activity relationship of a new class of potent VEGF receptor tyrosine kinase inhibitors: L.F. Hennequin, et al.; J. Med. Chem. 42, 5369 (1999), Abstract

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