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Z-Leu-Arg-Gly-Gly-AMC

BML-P801

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Substrate for ubiquitin C-terminal hydrolases (UCHs)

Fluorogenic substrate for ubiquitin C-terminal hydrolases (UCHs), including UCH-L3 and Isopeptidase T. Sequence is based on the C-terminal residues of ubiquitin. Ex.: 380 nm Em.: 460 nm.

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Product Details

Alternative Name	Z-LRGG-AMC, Ubiquitin C-terminal hydrolase substrate (fluorogenic), UCH substrate (fluorogenic)
Appearance	Lyophilized solid.
MW	692.8
Purity	≥95%
Sequence	Z-Leu-Arg-Gly-Gly-AMC (7-amino-4-methylcoumarin)
Solubility	Soluble in DMSO.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells: M. Oroń, et al.; Cell Rep. 40, 111428 (2022), Abstract
Activity-Dependent Degradation of the Nascentome by the Neuronal Membrane Proteasome: K.V. Ramachandran, et al.; Mol. Cell 71, 169 (2018), Abstract — Full Text

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Z-Leu-Arg-Gly-Gly-AMC

BML-P801

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

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