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Z-Gly-Gly-Leu-AMC

BML-ZW8505

10 citations

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A fluorogenic substrate for the chymotrypsin-like activity of the proteasome.

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Product Details

Appearance	White powder.
CAS	97792-39-7
Formula	C₂₈H₃₂N₄O₇
MW	536.6
Purity	≥98% (TLC)
Sequence	Z-GGL-AMC

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

The role of proteasome in muscle wasting of experimental arthritis: V.O.N. Teixeira, et al.; Adv. Rheumatol. 63, 14 (2023), Abstract
Cold temperature extends longevity and prevents disease-related protein aggregation through PA28γ-induced proteasomes: Lee, H. J., Alirzayeva, H., et al.; Nat. Aging 3, 546 (2023), Abstract
JADE family proteins regulate proteasome abundance and activity: Ebert, L. K., Bargfrede, S., et al.; bioRxiv , (2021)
The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury: Späth, M. R., Bartram, M. P., et al.; Kidney Int. 95, 333 (2019), Abstract
Matrine inhibits prostate cancer via activation of the unfolded protein response/endoplasmic reticulum stress signaling and reversal of epithelial to mesenchymal transition: J. Chang, et al.; Mol. Med. Rep. 18, 945 (2018), Abstract — Full Text
A leptospiral AAA+ chaperone-Ntn peptidase complex, HslUV, contributes to the intracellular survival of Leptospira interrogans in hosts and the transmission of leptospirosis: S.L. Dong, et al.; Emerg. Microbes Infect. 6, e105 (2017), Abstract — Full Text
The Architecture of the Anbu Complex Reflects an Evolutionary Intermediate at the Origin of the Proteasome System: A.C.D. Fuchs, et al.; Structure 25, 834 (2017), Abstract — Full Text
The immunoproteasomes are key to regulate myokines and MHC class I expression in idiopathic inflammatory myopathies: S. Bhattarai, et al.; J. Autoimmun. 75, 118 (2016), Application(s): Measurement of CT-L and CL proteasome activity, Abstract
Quantitative deep mapping of the cultured podocyte proteome uncovers shifts in proteostatic mechanisms during differentiation: M.M. Rinschen, et al.; Am. J. Physiol. Cell Physiol. 311, C404 (2016), Abstract
Irisflorentin improves α-synuclein accumulation and attenuates 6-OHDA-induced dopaminergic neuron degeneration, implication for Parkinson’s disease therapy: Y. M. Chen, et al.; Biomedicine (Taipei) 5, 4 (2015), Application(s): Assay, Abstract — Full Text

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Z-Gly-Gly-Leu-AMC

BML-ZW8505

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

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