Home Shop Z-DEVD-pNA

Z-DEVD-pNA

ALX-260-048

Datasheet
Manual
SDS
CofA

Already have an account?

Caspase substrate

Chromogenic substrate for caspase-3 with increased cell permeability. Also substrate for caspase-1, -4 and -7. λ_max of pNA is 400nm. Similar to Ac-DEVD-pNA except the N-terminus is blocked by a benzyloxycarbonyl (Z) moiety which may increase cell permeability.

Shipping: Available products typically ship within 24/48h, via priority shipping.

Do you need support? Contact Customer Service or Technical Support.

Online Account
Access or Create Your Account

Product Details

Alternative Name	Caspase-3 substrate (chromogenic)
Appearance	White powder.
Formula	C₃₂H₃₈N₆O₁₄
Formulation	Lyophilized.
MW	730.7
Peptide Content	70-90%
Purity	≥99% (HPLC)
Sequence	Z-Asp-Glu-Val-Asp-pNa (pNA = p-Nitroaniline)
Solubility	Soluble in DMSO or acetonitrile.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Keep cool and dry.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Propeptide-mediated inhibition of cognate gingipain proteinases: N.L. Hug, et al.; PLoS One 8, e65447 (2013), Abstract — Full Text
Activation of a CrmA-insensitive, p35-sensitive pathway in ionizing radiation-induced apoptosis: R. Datta, et al.; J. Biol. Chem. 272, 1965 (1997), Abstract
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis: D.W. Nicholson, et al.; Nature 376, 37 (1995), Abstract
Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE: Y.A. Lazebnik, et al.; Nature 371, 346 (1994), Abstract
Interleukin-1 beta converting enzyme: N.A. Thornberry; Methods Enzymol. 244, 615 (1994), Abstract

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Datasheet

Certificate of Analysis

Please enter the lot number as featured on the product label

Lot No. :

SDS

Enzo Life Science provides GHS Compliant SDS

English (EU) SDS

If your language is not available please fill out the SDS request form

Your Cart

Your Cart

Z-DEVD-pNA

ALX-260-048

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

Change Country

Tell us about You

Tell us about your paper

Tell us about You

Tell us about your project