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XL413 is a potent ATP-competitive inhibitor of the important DNA replication initiation kinase Cdc7 (DDK). It increases the efficiency of homology directed DNA repair in CRISPR-Cas9 gene editing. XL413 acted synergistically with other chemotherapy agents in various cancer models.
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RUO – Research Use Only |
|---|
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| CAS | 38966-21-1 |
|---|---|
| Couple Type | Inhibitor |
| Purity | ≥98% (TLC) |
| Alternative Name | (+)-3,3’,4’,5,7-Flavanpentol . H2O |
|---|---|
| CAS | 225937-10-0 |
| Purity | ≥98% (HPLC) |
| Alternative Name | (3R,4R)-4-[(3,4-Dimethoxyphenyl)methyl]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2-(3H)-furanone |
|---|---|
| CAS | 7770-78-7 |
| Couple Type | Inhibitor |
| Purity | ≥97% (HPLC) |
| Alternative Name | (3R,4R)-4-[(3,4-Dimethoxyphenyl)methyl]-3-[[4-(β-D-glucopyranosyloxy)-3-methoxyphenyl]methyl]dihydro-2(3H)-furanone |
|---|---|
| CAS | 20362-31-6 |
| Couple Type | Inhibitor |
| Purity | ≥95% (HPLC) |