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Calmodulin inhibitor

Binds to calmodulin, inhibiting Ca²⁺-calmodulin-regulated enzyme activity. Cell permeable.

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Alternative Name	N-(6-Aminohexyl)-1-naphthalenesulfonamide . HCl
Appearance	White to off-white solid.
CAS	61714-25-8
Couple Target	Calmodulin
Couple Type	Inhibitor
Formula	C₁₆H₂₂N₂O₂S . HCl
MW	342.9
Purity	≥98% (HPLC)
Solubility	Soluble in water, DMSO (20mg/ml), 100% ethanol (hot) or methanol (hot).

Use/Stability	As indicated on product label or CoA when stored as recommended. Stable for at least 1 year after receipt when stored at room temperature. Stock solutions are stable for for up to 6 months at -20°C.
Handling	Protect from light.
Long Term Storage	Ambient
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation: H. Hidaka, et al.; PNAS 78, 4354 (1981), Abstract — Full Text
[Pharmacology of calmodulin: calmodulin antagonist (author’s transl)]: H. Hidaka; Prot. Nucl. Acid Enz. 26, 977 (1981), Abstract
Hydrophobic regions function in calmodulin-enzyme(s) interactions.: T. Tanaka & H. Hidaka; J. Biol. Chem. 255, 11078 (1980), Abstract — Full Text

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