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Virodhamine

BML-FA036

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Cannabinoid receptor ligand

Endogenous cannabinoid which has been found to occur at concentrations 2 to 9 fold greater than anandamide in peripheral tissue. It acts as a full agonist at the CB₂ receptor and an antagonist at the CB₁ receptor.

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Product Details

Alternative Name	O-AEA, O-Arachidonoylethanolamine, Arachidonic acid-(2-aminoethyl)-ester, O-(2-aminoethyl)-5Z,8Z,11Z,14Z-eicosatetraenoic acid ester
Appearance	Yellow to brown oil.
CAS	443129-35-9
Couple Target	Cannabinoid receptor
Couple Type	Ligand
Formula	C₂₂H₃₇NO₂
MW	347.5
Purity	≥95% (TLC)
Solubility	Soluble in DMSO (45mg/ml), dimethyl formamide (40mg/ml) or ethanol (20mg/ml)

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended. Stable for at least 1 year after receipt when stored, as supplied, at -80°C and under an inert atmosphere.
Handling	Protect from oxygen. Keep under inert gas.
Long Term Storage	-80°C
Shipping	Dry Ice

Regulatory Status	RUO – Research Use Only

Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor: A.C. Porter, et al.; J. Pharmacol. Exp. Ther. 301, 1020 (2002), Abstract
Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor. Structure-activity relationship of 2-arachidonoylglycerol, ether-linked analogues, and related compounds: T. Sugiura, et al.; J. Biol. Chem. 274, 2794 (1999), Abstract

Last modified: May 29, 2024

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Virodhamine

BML-FA036

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Handling & Storage

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