Antibiotic that inhibits bacterial protein synthesis.
Virginiamycin S1 inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. It inactivates the 50S ribosome. When used in combination with Virginiamycin M1 it is synergistic. Virginiamycin is used as a performance promoter in animal husbandry. It is chemically modified to make therapeutic drugs such as quinupristin and dalfopristin.
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Last modified: May 29, 2024
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