A heterodimer composed of the catalytically active ubiquitin-conjugating enzyme UbcH13 and its catalytically inactive paralog hMms2, which lacks an active site cysteine residue.
The UbcH13/Mms2 complex catalyzes synthesis of Lys-linked, ubiquitin chains, which serve as non-proteolytic tags involved in error-free post-replicative DNA repair and NF-κB signal transduction.
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Regulatory Status |
RUO – Research Use Only |
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